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Stem cell tuning.Researchers from Tokyo Metropolitan University have quantified how mesenchymal stem cells respond to the mechanical stiffness of their environments. Specific proteins can be localized in the cell nucleus depending on the stiffness. Their findings will help scientists control the state of stem cells in medical treatments.Their work has been published in Analytical Sciences: https:\/\/doi.org\/10.2116\/analsci.20SCP02<\/a> #sciencenews<\/a> #biology<\/a> #genetics<\/a> #medicine<\/a><\/div>\n \n <\/i>\n J-STAGE<\/div>\n \n
Designing Elastic Modulus of Cell Culture Substrate to Regulate YAP and RUNX2 Localization for Controlling Differentiation of Human\u2026<\/div>\n
To establish a guideline for the design of cell culture substrates to control human mesenchymal stem cell (MSC) differentiation, we quantitatively cha \u2026<\/div>\n<\/a>\n
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Safe to drink.Micropollutants such as steroid hormones contaminate drinking water worldwide and pose a significant threat to human health. Scientists at Karlsruhe Institute of Technology have developed a new chemical process to remove hormones using photocatalysis to transform the pollutants into safe products.The results can be viewed in Applied Catalysis B: Environmental: https:\/\/www.sciencedirect.com\/science\/article\/abs\/pii\/S092633732100223X?via%3Dihub<\/a> #sciencenews<\/a> #environment<\/a><\/div>\n \n <\/i>\n Sciencedirect<\/div>\n \n
Photodegradation of steroid-hormone micropollutants in a flow-through membrane reactor coated with Pd(II)-porphyrin<\/div>\n
The efficient degradation of steroid-hormone micropollutants is demonstrated in a single-pass, continuous operation of the photocatalytic membrane rea\u2026<\/div>\n<\/a>\n
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Light out of thin air.Most commercial chemicals require catalysts to produce, which normally take the form of metal nanoparticles. A team at Vienna University of Technology have shown how the atomic scale surface structures of such catalysts can critically influence their reactive properties. They visualise the oxidation of hydrogen on a single rhodium nanoparticle in real time.Their insights are published in Science: https:\/\/science.sciencemag.org\/content\/early\/2021\/05\/19\/science.abf8107<\/a> #sciencenews<\/a> #nano<\/a> #physics<\/a><\/div>\n \n \n
Science<\/div>\n <\/i>\n Resolving multifrequential oscillations and nanoscale interfacet communication in single-particle catalysis<\/div>\n
In heterogeneous catalysis research, the reactivity of the individual nanofacets of single particle is typically not resolved. We applied in situ field electron microscopy (FEM) to the apex of a curved rhodium crystal (radius of 650 nanometers), providing\u2026<\/div>\n<\/a>\n
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Plastic to combat pollution. Biodegradable plastics are better for the environment, but their rapid degradation means they can\u2019t be recycled. Researchers from the University of Canterbury have developed a method to convert the plastics to a foam that can be reused for insulation or flotation devices.Their method is described in the journal Physics of Fluids: https:\/\/aip.scitation.org\/doi\/10.1063\/5.0050649<\/a>#sciencenews<\/a> #environment<\/a> #chemistry<\/a><\/div>\n \n \n
AIP Publishing<\/div>\n <\/i>\n Recycling and rheology of poly(lactic acid) (PLA) to make foams using supercritical fluid<\/div>\n
Biodegradable plastics are thought to be the possible directions in managing plastic pollutions. Unfortunately, they are not recycled in most countries since they are designed to decompose even tho...<\/div>\n<\/a>\n
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Recycling electric vehicle batteries.University of Leicester researchers have developed an ultrasonic delamination technique to controllably separate the different metals used in lithium-ion batteries, improving the yield and purity of the recovered materials.Their analysis is detailed in Green Chemistry: http:\/\/dx.doi.org\/10.1039\/D1GC01623G<\/a>#sciencenews<\/a> #chemistry<\/a> #environment<\/a><\/div>\n \n \n
pubs.rsc.org<\/div>\n <\/i>\n Lithium ion battery recycling using high-intensity ultrasonication<\/div>\n
Decarbonisation of energy will rely heavily, at least initially, on the use of lithium ion batteries for automotive transportation. The projected volumes of batteries necessitate the development of fast and efficient recycling protocols. Current methods are\u2026<\/div>\n<\/a>\n
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Down the nano-hole.A sensing technique developed at the University of Cambridge has been used to reveal the fundamental physics governing the transport of DNA threads through nanopores. They assembled DNA molecules with \u2018bumps\u2019 at specific locations that could be used to track the passage of the molecule.The study is published in Nature Physics: http:\/\/dx.doi.org\/10.1038\/s41567-021-01268-2<\/a> #sciencenews<\/a> #genetics<\/a> #nano<\/a><\/div>\n \n <\/i>\n Nature Physics<\/div>\n \n
Dynamics of driven polymer transport through a nanopore<\/div>\n
Nature Physics - A study of the dynamics of polymer translocation through synthetic nanopores provides a direct observation of tension propagation—a non-equilibrium description of the...<\/div>\n<\/a>\n
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Life beneath Antarctic ice.Pioneering research at the University of Bristol has shown the erosion of ancient sediments found deep beneath Antarctic ice is a vital source of the nutrients and energy needed to sustain for subglacial microbial life. Their lab-based experiments replicated the conditions in Lake Whillans, 800m underneath Antarctica, where crushed sediments could release methane, carbon dioxide, and hydrogen in substantial concentrations.Learn about their insight in Communications Earth & Environment: https:\/\/www.nature.com\/articles\/s43247-021-00202-x?proof=t<\/a> #sciencenews<\/a> #environment<\/a><\/div>\n \n <\/i>\n Nature<\/div>\n \n
Subglacial erosion has the potential to sustain microbial processes in Subglacial Lake Whillans, Antarctica<\/div>\n
Communications Earth & Environment - The crushing and wetting of rocks by erosion under glaciers produces chemical compounds that could fuel microbial activity, as demonstrated by experiments...<\/div>\n<\/a>\n
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The earthworm in a new light.By combining novel imaging techniques, a team of researchers from the Max Planck Institute for Marine Microbiology has imaged the exciting variety of chemical interactions that take place inside the earthworm. Their chemo-histo-tomography method combines chemical imaging of the metabolites using mass spectrometry with micro-computed X-ray tomography of the microanatomy of the animal.The work has recently been published in PNAS: http:\/\/dx.doi.org\/10.1073\/pnas.2023773118<\/a> #sciencenews<\/a> #microscopy<\/a> #biology<\/a> #microbiology<\/a><\/div>\n \n \n
PNAS<\/div>\n <\/i>\n Connecting structure and function from organisms to molecules in small-animal symbioses through chemo-histo-tomography<\/div>\n
Metabolites mediate the establishment and persistence of most interkingdom symbioses. Still, to pinpoint the metabolites each partner displays upon interaction remains the biggest challenge in studying multiorganismal assemblages. Addressing this challenge\u2026<\/div>\n<\/a>\n
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Visualizing atomic-scale structures with the optical force.Researchers from Osaka University have achieved the first ever sub-nanometre resolution in photoinduced atomic force microscopy. They eliminated noise sources to map out the forces acting on quantum dots in 3D with a precision never previously achieved. Their work has been published in Nature Communications: https:\/\/doi.org\/10.1038\/s41467-021-24136-2<\/a> #sciencenews<\/a> #microscopy<\/a> #quantum<\/a><\/div>\n \n <\/i>\n Nature<\/div>\n \n
Optical force mapping at the single-nanometre scale<\/div>\n
Nature Communications - Direct visualisation of 3D vector distributions of photoinduced fields can shed light on the optical and mechanical behaviour of different materials. Here, the authors...<\/div>\n<\/a>\n
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A mouse in a Petri dish.University of Virginia biologists have grown the most sophisticated in-vitro mammal model known from stem cells. The tiny mouse embryo has a heart that beats, and its muscles, blood vessels, gut, and nervous system are beginning to develop. The model will aid understanding of mammalian development to help grow new tissues and organs for transplants.Their latest results are published in Nature Communications: http:\/\/dx.doi.org\/10.1038\/s41467-021-23653-4<\/a> #sciencenews<\/a> #biology<\/a> #embriology<\/a><\/div>\n \n <\/i>\n Nature Communications<\/div>\n \n
Construction of a mammalian embryo model from stem cells organized by a morphogen signalling centre<\/div>\n
Following instruction by a morphogen secreting centre, aggregates of mouse embryonic stem cells develop into embryo-like structures organized around an axial mesoderm, which show extensive...<\/div>\n<\/a>\n
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On the brink of chaos.Scientists at the University of Sydney and Japan's National Institute for Material Science have discovered that an artificial network of nanowires can be tuned to respond in a brain-like way to electrical stimuli. By keeping the network of nanowires in a chaotic, brain-like state optimized its performance.Their insights are published in Nature Communications: http:\/\/dx.doi.org\/10.1038\/s41467-021-24260-z<\/a> #sciencenews<\/a> #nano<\/a> #AI<\/a><\/div>\n \n <\/i>\n Nature Communications<\/div>\n \n
Avalanches and edge-of-chaos learning in neuromorphic nanowire networks<\/div>\n
Neuromorphic nanowire networks are found to exhibit neural-like dynamics, including phase transitions and avalanche criticality. Hochstetter and Kuncic et al. show that the dynamical state at the...<\/div>\n<\/a>\n
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Quantum random numbers.Most random numbers aren\u2019t truly random. However, using quantum computers can achieve levels of randomness only limited by the basic laws of quantum physics. Researchers at the University of Science and Technology of China have built the fastest known real-time quantum random number generator by combining state-of-the-art photonic integration with advanced post-processing technologies.Their machine is described in Applied Physics Letters: https:\/\/aip.scitation.org\/doi\/10.1063\/5.0056027<\/a>#sciencenews<\/a> #Quantum<\/a> #photonic<\/a><\/div>\n \n \n
AIP Publishing<\/div>\n <\/i>\n 18.8 Gbps real-time quantum random number generator with a photonic integrated chip<\/div>\n
Quantum random number generators (QRNGs) can produce true random numbers. Yet, the two most important QRNG parameters highly desired for practical applications, i.e., speed and size, have to be com...<\/div>\n<\/a>\n
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Environmental brain effects.A stimulating environment helps to keep the hippocampus young through molecular mechanisms affecting gene regulation. Studies in mice by the German Centre for Neurodegenerative Diseases provide clues as to why an active, varied lifestyle can help preserve mental acuity in old age.Their insights are described in Nature Communications: http:\/\/dx.doi.org\/10.1038\/s41467-021-23993-1<\/a> #sciencenews<\/a> #environment<\/a> #biology<\/a><\/div>\n \n <\/i>\n Nature<\/div>\n \n
Environmental enrichment preserves a young DNA methylation landscape in the aged mouse hippocampus<\/div>\n
Nature Communications - Decline of brain function during aging is associated with epigenetic changes, including DNA methylation. Here the authors provide evidence that environmental enrichment...<\/div>\n<\/a>\n
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Viruses fighting cancer.Researchers at the Luxembourg Institute of Health have developed a cancer-destroying virus that binds to laminins on the surface of cancer cells to gain entry to the cell before ultimately killing it. The viruses hold significant potential for deployment in targeted cancer therapies.The work has recently been published in Nature Communications: http:\/\/dx.doi.org\/10.1038\/s41467-021-24034-7<\/a> #sciencenews<\/a> #medicine<\/a> #health<\/a><\/div>\n \n <\/i>\n Nature<\/div>\n \n
Oncolytic H-1 parvovirus binds to sialic acid on laminins for cell attachment and entry<\/div>\n
Nature Communications - Rat H-1 parvovirus (H-1PV) is in clinical development for oncolytic therapy. Here, Kulkarni et al. identify LAMC1 as a modulator of H-1PV cell attachment and entry and find...<\/div>\n<\/a>\n
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Fighting Alzheimer\u2019s.Researchers from the University of Barcelona are working to develop new compounds that can bind to specific receptors in the brain linked to Alzheimer\u2019s disease. Their studies in mice improved the cognitive deficit and the biomarkers related to the disease.Their work has been published in the European Journal of Medicinal Chemistry: https:\/\/www.sciencedirect.com\/science\/article\/abs\/pii\/S0223523421003895?via%3Dihub<\/a> #sciencenews<\/a> #biology<\/a> #neuroscience<\/a><\/div>\n \n <\/i>\n Sciencedirect<\/div>\n \n
Benzofuranyl-2-imidazoles as imidazoline I2 receptor ligands for Alzheimer's disease<\/div>\n
Recent findings unveil the pharmacological modulation of imidazoline I2 receptors (I2-IR) as a novel strategy to face unmet medical neurodegenerative \u2026<\/div>\n<\/a>\n
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Kirigami cameras.University of Houston researchers have developed a kirigami-inspired camera with a curvy, adaptable imaging sensor that could improve image quality in endoscopes, night-vision goggles, artificial compound eyes and fish-eye cameras.Learn about their system in Nature Electronics: https:\/\/www.nature.com\/articles\/s41928-021-00600-1<\/a> #sciencenews<\/a> #sensors<\/a> #physics<\/a> #optics<\/a><\/div>\n \n <\/i>\n Nature Electronics<\/div>\n \n
Curvy, shape-adaptive imagers based on printed optoelectronic pixels with a kirigami design<\/div>\n
Curvy and shape-adaptive imagers with high pixel fill factors and tunable focusing power can be created by transferring an array of ultrathin silicon optoelectronic pixels with a kirigami design...<\/div>\n<\/a>\n
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Vision in mice.Mouse vision was thought to be different to that of humans because humans have a region of the retina specialized for fine details called the 'fovea' whereas mice do not. However, researchers from the Netherlands Institute of Neuroscience have shown that the visual cortex of mice in fact contains a region of enhanced visual sensitivity - the 'focea'. This makes mice a better model for human vision than previously predicted.The results can be read in Nature Communications: http:\/\/dx.doi.org\/10.1038\/s41467-021-24311-5<\/a> #sciencenews<\/a> #biology<\/a> #neuroscience<\/a><\/div>\n \n <\/i>\n Nature Communications<\/div>\n \n
Mouse visual cortex contains a region of enhanced spatial resolution<\/div>\n
Nature Communications - The representation of space in mouse visual cortex was considered to be relatively uniform. The authors show that mice have improved visual resolution in a cortical region...<\/div>\n<\/a>\n
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Synthesising cancer treatments.Rice University chemists have developed a simplified method for the facile synthesis of halichondrin B and related compounds. This important molecule has potent anti-tumour properties of great interest to medical research.Their insights are published in the Journal of the American Chemical Society: http:\/\/dx.doi.org\/10.1021\/jacs.1c05270<\/a> #sciencenews<\/a> #chemistry<\/a> #cancer<\/a><\/div>\n \n \n
ACS Publications<\/div>\n <\/i>\n A Reverse Approach to the Total Synthesis of Halichondrin B<\/div>\n
A new strategy is described for the total synthesis of halichondrin B featuring reversal of the sequential construction of a number of its cyclic ethers from the classical approach by instead forming C\u2013O bonds first followed by C\u2013C bond formation. Employing\u2026<\/div>\n<\/a>\n
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Gravitational waves from black holes swallowing neutron stars.Scientists from LIGO, Virgo, and KAGRA have detected gravitational waves generated over 900 million light-years away by the merging of a neutron star with a black hole, broadening the field of gravitational wave astronomy to another astrophysical system.The preliminary report has been published in Astrophysical Journal Letters: https:\/\/iopscience.iop.org\/article\/10.3847\/2041-8213\/ac082e<\/a> #sciencenews<\/a> #astrophysics<\/a><\/div>\n\n
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Sensitive coronavirus testing. A new corona test developed at the University Hospital Bonn can simultaneously analyse a large number of swabs using sequencing technology and has a similarly high sensitivity to the common qPCR tests. The innovative method offers great potential for rapid systematic testing without the drawbacks of most methods.The test is described in Nature Biotechnology: https:\/\/www.nature.com\/articles\/s41587-021-00966-9<\/a> #sciencenews<\/a> #coronavirus<\/a> #molecularbiology<\/a><\/div>\n \n \n
Nature<\/div>\n <\/i>\n LAMP-Seq enables sensitive, multiplexed COVID-19 diagnostics using molecular barcoding<\/div>\n
Nature Biotechnology - SARS-CoV-2 detection with LAMP-Seq combines isothermal amplification and barcoding with high-throughput sequencing.<\/div>\n<\/a>\n
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